Students pursuing post-secondary education should never face discrimination, harassment, or exclusion on their campuses. Yet on many Ontario university campuses, Two Spirit and LGBTQ+ students face such realities and are marginalized because of who they are. In some cases, these students become the targets of deliberate, hate-motivated actions, and in other instances, the blame lies in ignorance or apathy. It is OUSA’s hope that the recommendations provided in this paper will contribute to improving access to and safety in postsecondary education for Two Spirit and LGBTQ+ students.